## Abstract The aim of this study was to develop a standardized effective thrombogenic arterial anastomosis model, as usually encountered in clinical practice, and to offer a detailed evaluation of the antithrombotic effect of thrombin's direct inhibitors, antithrombin III and hirudin, as locally a
Microvascular repair following local crush and avulsion vascular injury
β Scribed by Brian C. Cooley; Frederik C. Hansen
- Book ID
- 102512485
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- English
- Weight
- 315 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0738-1085
No coin nor oath required. For personal study only.
β¦ Synopsis
A model has been developed demonstrating intimal damage resulting from a combined crush and avulsion injury to the femoral artery of the rat. Revascularization after traumatization is accomplished with microvascular anastomosis of the severed ends. Vascular patency rates at 2 and 7 days postoperatively are low (0-25%) in comparison with control groups (90-100%). A high correlation is found between patency tests performed at 20 minutes and at 2 days after blood flow re-establishment. Systemically administered heparin improves traumatized-vessel patency dramatically.
π SIMILAR VOLUMES
The failure rate of replantations following a crush-avulsion type injury is high. This study has been designed to reproduce an effective standardized crush-avulsion injury model to the femoral artery of the rat and evaluate the antithrombotic efficacy of systemic intravenous administration of recomb
## Abstract Vein thrombosis is often encountered in microsurgery, especially in the case of crushβavulsion injuries. The aim of this study was to investigate the effect of systemic administration of recombinant tissueβtype plasminogen activator (rtβPA) on the patency of the femoral vein of the rat,
## Abstract Insufficiency of skeletal muscle regeneration is often accompanied with functional deficiencies. The goal of our study was to assess the restoration of peripheral muscle upon injury of different severity. Blunt crush injury of the soleus muscle in rats was induced by a clamp and stepwis