✦ LIBER ✦

Microscale synthesis of volatile, 14C-labelled acid chlorides

✍ Scribed by Howard Parnes; Steve De Keczer

Publisher: John Wiley and Sons
Year: 1985
Tongue: French
Weight: 195 KB
Volume: 22
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.2580220310

No coin nor oath required. For personal study only.

✦ Synopsis

A method for the microscale (one m o l e ) synthesis of volatile, 14C-labelled acid chlorides from Ba14C03 using vacuum line techniques is described. By a judicious choice of reagents, desired intermediates and products may be isolated in high yield by simple vacuum transfer techniques without fractionation.

📜 SIMILAR VOLUMES

The synthesis of 14C-labeled chlorogenic

The synthesis of 14C-labeled chlorogenic acid

✍ J. F. Debardeleben; L. C. Teng 📂 Article 📅 1970 🏛 John Wiley and Sons 🌐 French ⚖ 276 KB 👁 1 views

14C-labeled chlorogenic acid (specijic activity 30.6 nCilmg) was synthesized by reaction of diphenylmethyl-I-0-ethoxy-carbonyl- 4,5-0-isopropylidenequinate ( V ) with 0,O-dimethylcarbonyl caffeoyl chloride-u-14C (VIII) followed by selective hydrolysis of the protecting groups.

synthesis of 14C-labelled tranexamic aci

synthesis of 14C-labelled tranexamic acid [trans-amino-(14C-methyl)-cyclohexane carboxylic acid]

✍ Jan Lundström; Gertrud Westin-Sjödahl; N. Åke Jönsson 📂 Article 📅 1976 🏛 John Wiley and Sons 🌐 French ⚖ 195 KB

An improved synthesis of [1-14C]-labelle

An improved synthesis of [1-14C]-labelled 2-butynedioic acid, succinic acid and succinyl chloride

✍ Vijayalakshmi V. Somayaji; Tse W. Hall; Leonard I. Wiebe; Edward E. Knaus 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 French ⚖ 236 KB

Synthesis of 14C-labelled satigrel

✍ Shigeru Tanaka; Youji Yamagishi; Kazutomi Kusano; Tsutomu Yoshimura 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 French ⚖ 222 KB 👁 1 views

14C-Labelled satigrel, or 4-cyano-5-(4'-methoxy tring-U-14CI phenyl)-5-(4"methoxyphenyl)-4-pentenoic acid was synthesized for drug metabolism and pharmacokinetic studies using 4,4'-diniethoxy [ring-U-W ] benzophenone as the starting material. The radiochemical yield was 10.0%. The specific radioacti

Synthesis of 14C-labelled crotamiton

✍ Naba K. Chaudhuri; Sudhakar V. Potdar; Thomas J. Ball 📂 Article 📅 1982 🏛 John Wiley and Sons 🌐 French ⚖ 266 KB

The synthesis of 14C-labelled crotamiton, which is a fungicide, an insecticide as well as a scabicide is described. Starting from 2-bromonitrobenzene and Cu14CN, 2-toluidine, labelled with 14C at the methyl group was prepared by the following sequence of reactions : N O ~-C ~H L + -~~C O O H

Synthesis of 14C-labelled aminoguanidine

✍ Theodore W. C. Lo; Paul J. Thornalley 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 French ⚖ 208 KB

## Abstract [^14^C]Aminoguanidine was synthesized by the reaction of hydrazine sulphate with barium [^14^C]cyanamide in a one‐step synthesis, and conveniently isolated by crystallization as the bicarbonate salt. The yield was 32%.