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MicroRNA-125b-1accelerates a C-terminal mutant of C/EBPα (C/EBPα-Cm)-induced myeloid leukemia

✍ Scribed by Yutaka Enomoto, Jiro Kitaura, Masaya Shimanuki…

Book ID
120955154
Publisher
Carden Jennings Publishing
Year
2012
Tongue
English
Weight
471 KB
Volume
96
Category
Article
ISSN
0925-5710

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✍ Tomoko Nanri; Naokuni Uike; Toshiro Kawakita; Eisaku Iwanaga; Hiroaki Mitsuya; N 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 232 KB

## Abstract C/EBPα plays an essential role as a transcription factor in myeloid cell differentiation. Here, we describe a Japanese family in which two individuals with acute myeloid leukemia (AML) and one healthy individual had an identical 4‐base pair insertion in the N‐terminal region of __CEBPA_