Sox4 Is a Key Oncogenic Target in C/EBPα Mutant Acute Myeloid Leukemia
✍ Scribed by Zhang, Hong; Alberich-Jorda, Meritxell; Amabile, Giovanni; Yang, Henry; Staber, Philipp B.; Di Ruscio, Annalisa; Welner, Robert S.; Ebralidze, Alexander; Zhang, Junyan; Levantini, Elena; Lefebvre, Véronique; Valk, Peter J.M.; Delwel, Ruud; Hoogenkamp, Maarten; Nerlov, Claus; Cammenga, Jörg; Saez, Borja; Scadden, David T.; Bonifer, Constanze; Ye, Min; Tenen, Daniel G.
- Book ID
- 122186669
- Publisher
- Elsevier Science
- Year
- 2014
- Tongue
- English
- Weight
- 60 KB
- Volume
- 25
- Category
- Article
- ISSN
- 1535-6108
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## Abstract A myeloid leukemia cell line designated Kasumi‐6 was established from the bone marrow cells of an individual with acute myeloid leukemia, subtype M2. Both the original leukemic cells and the Kasumi‐6 cell line harbor a hemizygous point mutation in the gene encoding the CCAAT/enhancer bi