The role of self-peptides in influencing the development of the T-cell repertoire has been the focus of recent studies. The findings suggest that the recognition of self-peptides bound to MHC proteins in the thymus is part of the thymic self-recognition process that results in selective maturation,
MHC antigens and cancer: implications for T-cell surveillance
β Scribed by Michael J Browning; Walter F. Bodmer
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 787 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0952-7915
No coin nor oath required. For personal study only.
β¦ Synopsis
Evidence for a direct involvement of cell-mediated immune mechanisms in the control of human tumours remains sketchy. The past year, however, has seen advances in our understanding of the relationship between the immune system and tumour cells, and has given rise to new prospects for immunological treatment and the prevention of cancers.
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