Evidence for a direct involvement of cell-mediated immune mechanisms in the control of human tumours remains sketchy. The past year, however, has seen advances in our understanding of the relationship between the immune system and tumour cells, and has given rise to new prospects for immunological t
β¦ LIBER β¦
Role of MHC and antigens in T-cell development
β Scribed by Kenneth M. Murphy
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 834 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0952-7915
No coin nor oath required. For personal study only.
β¦ Synopsis
The role of self-peptides in influencing the development of the T-cell repertoire has been the focus of recent studies. The findings suggest that the recognition of self-peptides bound to MHC proteins in the thymus is part of the thymic self-recognition process that results in selective maturation, or positive selection of T cells.
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