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✦   LIBER   ✦

Single T cell probes for antigen/MHC expression

✍ Scribed by Nilabh Shastri

Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
473 KB
Volume
7
Category
Article
ISSN
0952-7915

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✦ Synopsis

T-cell receptor binding to the antigen/MHC ligand on the surface of antigen-presenting cells is the central event in T-cell activation. Methods have been developed for measuring this recognition event in single T cells and have allowed their use as 'probes' for antigen/MHC expression. Single cell assays have allowed analysis of early events in T-cell activation, and of unknown ligands recognized by the T-cell receptor.

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