The sole application of an inhibitor of the dipeptidyl peptidase DP IV (also DP 4, CD26, DPP-IV or DPP-4) to a mammal subsequently leading to improved glucose tolerance marks a major breakthrough in metabolic research bearing the potential of a new revolutionary diabetes therapy. This was demonstrat
✦ LIBER ✦
Metformin inhibits dipeptidyl peptidase IV activity in type 2 diabetes
✍ Scribed by J. R. Lindsay; N. Duffy; A. M. McKillop; J. Ardill; F. P. M. O’Harte; P. R. Flatt; P. M. Bell
- Publisher
- Springer-Verlag
- Year
- 2002
- Tongue
- English
- Weight
- 231 KB
- Volume
- 171
- Category
- Article
- ISSN
- 1863-4362
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Type 2 diabetes—Therapy with dipeptidyl
✍
Hans-Ulrich Demuth; Christopher H.S. McIntosh; Raymond A. Pederson
📂
Article
📅
2005
🏛
Elsevier Science
🌐
English
⚖ 803 KB
Hyperglycaemia increases dipeptidyl pept
✍
E. Mannucci; L. Pala; S. Ciani; G. Bardini; A. Pezzatini; I. Sposato; F. Cremasc
📂
Article
📅
2005
🏛
Springer
🌐
English
⚖ 112 KB
MK-0431 : Agent for Type 2 Diabetes and
✍
L. A. Sorbera; J. Castaner
📂
Article
📅
2006
🏛
John Wiley and Sons
⚖ 8 KB
👁 1 views
Dipeptidyl peptidase IV inhibitors in di
✍
Martin C. Michel; Eric Fliers; Cornelis J. F. Van Noorden
📂
Article
📅
2008
🏛
Springer-Verlag
🌐
English
⚖ 88 KB
Optimization of 1,4-Diazepan-2-one-Conta
✍
Gui-Bai Liang; et al. et al.
📂
Article
📅
2007
🏛
John Wiley and Sons
⚖ 24 KB
👁 1 views
ChemInform Abstract: The Asymmetric Synt
✍
Feng Liu; Wansheng Yu; Wenhua Ou; Xiaoke Wang; Libo Ruan; Yiming Li; Xijiang Pen
📂
Article
📅
2010
🏛
John Wiley and Sons
⚖ 23 KB
👁 1 views
## Abstract Key step in the improved synthetic pathway to sitagliptin (VII), a new DPP‐IV inhibitor for the treatment of type 2 diabetes mellitus, is an asymmetric Michael addition to give intermediate (IV).