Metal ion promoted oxidation of a methyl group of 2,3-dihydro-2,2,4-trimethyl-1H-1,5-benzodiazepine
✍ Scribed by Zoltán Szeverényi; László I. Simándi
- Publisher
- Elsevier Science
- Year
- 1989
- Weight
- 332 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0304-5102
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📜 SIMILAR VOLUMES
In the title compound, C 22 H 18 C l2 N 2 , the seven-membered heterocyclic ring is in a boat-shaped conformation. The molecules are linked by N-HÁ Á ÁN hydrogen bonding into one-dimensional chains along the [010] direction.
## Abstract Two benzodiazepines, Diazepam and Flunitrazepam, labeled with carbon‐14 in position 5 of the diazepine ring have been synthesized. Use of a condensation between iminochlorides and ^14^C‐benzonitriles, followed by exhaustive methylation of the resulting quinazolines and hydrolyses is des
## Abstract The synthesis of specifically labeled 2,5,8‐trimethyl‐3,4‐dihydro‐1(2H)‐naphthalenone‐2‐d and 3,5,8‐trimethyl‐3,4‐dihydro‐1(2H)‐naphthalenone‐2,2‐d~2~ through α‐proton exchange using neat trifluoroacetic acid‐d is described.