Oxidation of a methyl to a formyl group in 2,3-dihydro-2,2,4-trimethyl-1H-1,5-benzodiazepine by O2 in the presence of metal ions
✍ Scribed by Zoltán Szeverényi; László I. Simándi; Ryszard Iwanejko
- Publisher
- Elsevier Science
- Year
- 1991
- Weight
- 230 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0304-5102
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Reaction of acetaldehyde with the trianion of 4,6-dimethylnonane-3,5, 7-trione followed by acidification yielded a stereoisomeric mixture of the pheromone of Stegobium paniceum L. The sex pheromone produced by the female drugstore beetle, Stegobium paniceum L., was recently isolated,' and the struct
o-Nitrophenylazide was treated with the low-valent titanium reagent derived from the TiCl 4 /Sm system to produce the intermediate 2 in situ, which was a 'living' double-anion and reacted readily with ketones containing active methyl or methylene groups to afford 2,3-dihydro-1H-1,5-benzodiazepines i