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Acylation of 2-Methyl-2,4-diphenyl-2,5-dihydro-1H-1,5-benzodiazepine by Succinic Anhydride.

✍ Scribed by V. A. Chebanov; E. A. Muravyeva; K. M. Kobzar

Publisher
John Wiley and Sons
Year
2003
Weight
69 KB
Volume
34
Category
Article
ISSN
0931-7597

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## Abstract Two benzodiazepines, Diazepam and Flunitrazepam, labeled with carbon‐14 in position 5 of the diazepine ring have been synthesized. Use of a condensation between iminochlorides and ^14^C‐benzonitriles, followed by exhaustive methylation of the resulting quinazolines and hydrolyses is des