Metabolism of 14c-labeled glutamic acid and pyroglutamic acid in animals
β Scribed by Winthrop E. Lange; Edward F. Carey
- Publisher
- John Wiley and Sons
- Year
- 1966
- Tongue
- English
- Weight
- 312 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract A widely used herbicide, 2,2βdichloropropionic acid (dalapon), was synthesized with ^14^Cβlabeling in the Cβ1 or Cβ2 positions. The carboxyl labeled material was prepared in 55% yield by carbonation of 1,1βdichloroβethyllithium at approximately β104Β°. Starting with trichloroacetic acid,
14C-labeled chlorogenic acid (specijic activity 30.6 nCilmg) was synthesized by reaction of diphenylmethyl-I-0-ethoxy-carbonyl- 4,5-0-isopropylidenequinate ( V ) with 0,O-dimethylcarbonyl caffeoyl chloride-u-14C (VIII) followed by selective hydrolysis of the protecting groups.
Perf1 uoro-n-octanoic acid (PFOA) and perf luoro-n-decanoic acid (PFOA), two yddely used industrial products, have been synthesized with C-labeling in the C-1 position. The carboxyl labeled materials were prepared in 48% and 53% yield by carbonation of perfluoroheptyllithium and perfluorononyllithiu