Meta-analysis in clinical trials
โ Scribed by Rebecca DerSimonian; Nan Laird
- Book ID
- 119143300
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 668 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0197-2456
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Randomized trials are effective and usually unbiased for showing the average results in a selected outcome variable for treatment A versus treatment B, and meta-analyses produce an average of these averages. The results of both the trials and meta-analyses are often pragmatically unsatisfactory, how
In this paper we discusa empirical Bayes methods for combining evidence from a series of clinical experiments comparing two treatments. The approach is bawd on a random effects model for the treatment effects. We describe two nonparametric empirical Bayes procedures for estimating the effect sizes i
The randomized clinical trial is the gold standard methodology for evaluating treatment interventions. The randomized trial is a prospective experimental study, the embodiment of the scientific method applied to the clinic. Both organizational and ethical considerations encourage the use of formal c