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Commentary on meta-analysis in clinical trials

✍ Scribed by Jesse Berlin; Thomas C. Chalmers


Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
266 KB
Volume
8
Category
Article
ISSN
0270-9139

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πŸ“œ SIMILAR VOLUMES


META-ANALYSIS AND META-ANALYTIC MONITORI
✍ ALVAN R. FEINSTEIN πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 627 KB

Randomized trials are effective and usually unbiased for showing the average results in a selected outcome variable for treatment A versus treatment B, and meta-analyses produce an average of these averages. The results of both the trials and meta-analyses are often pragmatically unsatisfactory, how

THE ROLE OF META-ANALYSIS IN MONITORING
✍ COLIN B. BEGG πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 665 KB

The randomized clinical trial is the gold standard methodology for evaluating treatment interventions. The randomized trial is a prospective experimental study, the embodiment of the scientific method applied to the clinic. Both organizational and ethical considerations encourage the use of formal c

META-ANALYSIS IN THE DESIGN AND MONITORI
✍ REBECCA DERSIMONIAN πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 828 KB

Results from external studies often play an important role in many aspects of a clinical trial. Their incorporation into the decision making process of a trial, however, is rarely conducted in a formal manner. This conference will address what formal role, if any, meta-analytic summaries of external

CHANGES IN CLINICAL TRIALS MANDATED BY T
✍ THOMAS C. CHALMERS; JOSEPH LAU πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 460 KB πŸ‘ 2 views

Service on the Data Monitoring Committee of the CPEP (Calcium for Pre-eclampsia Prevention) has led us to four conclusions about clinical trials which we should like to present to this gathering of biostatisticians for their reactions: (i) meta-analyses of the pertinent published trials of the same