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Commentary on ‘Alpha calculus in clinical trials: considerations and commentary for the new millennium’

✍ Scribed by Robert T. O'Neill

Publisher: John Wiley and Sons
Year: 2000
Tongue: English
Weight: 73 KB
Volume: 19
Category: Article
ISSN: 0277-6715
DOI: 10.1002/(sici)1097-0258(20000330)19:6<785::aid-sim520>3.0.co;2-k

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Alpha calculus in clinical trials: consi

Alpha calculus in clinical trials: considerations and commentary for the new millennium

✍ Lemuel A. Moyé 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 103 KB 👁 1 views

Regardless of whether a statistician believes in letting a data set speak for itself through nominal p-values or believes in strict alpha conservation, the interpretation of experiments which are negative for the primary endpoint but positive for secondary endpoints is the source of some angst. The

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✍ Gary G. Koch 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 43 KB 👁 1 views

The paper by MoyÃ e [1] provides useful discussion for some important statistical issues concerning the possibly complicated ways in which multiple comparisons across primary and secondary endpoints can a ect the results from clinical trials. How to balance tolerable in ation of type I error against

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✍ Lemuel A. Moyé 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 47 KB 👁 2 views

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