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Response to commentaries on ‘Alpha calculus in clinical trials: considerations for the new millennium’

✍ Scribed by Lemuel A. Moyé

Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
47 KB
Volume
19
Category
Article
ISSN
0277-6715

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📜 SIMILAR VOLUMES

Alpha calculus in clinical trials: consi
Alpha calculus in clinical trials: considerations and commentary for the new millennium
✍ Lemuel A. Moyé 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 103 KB 👁 1 views

Regardless of whether a statistician believes in letting a data set speak for itself through nominal p-values or believes in strict alpha conservation, the interpretation of experiments which are negative for the primary endpoint but positive for secondary endpoints is the source of some angst. The

Discussion for ‘Alpha calculus in clinic
Discussion for ‘Alpha calculus in clinical trials: considerations and commentary for the new millennium’
✍ Gary G. Koch 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 43 KB 👁 1 views

The paper by Moyà e [1] provides useful discussion for some important statistical issues concerning the possibly complicated ways in which multiple comparisons across primary and secondary endpoints can a ect the results from clinical trials. How to balance tolerable in ation of type I error against