Evidence of delayed progression is the primary mechanism for demonstrating therapeutic e cacy in clinical trials in Alzheimer's disease. In the major trials of therapeutic treatment of AD, to date, measures based on clinical judgement and cognitive performance, instead of mortality, have been used a
Role of meta-analysis of clinical trials for Alzheimer's disease
✍ Scribed by Jesús M. López Arrieta
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 108 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0272-4391
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Much of the literature is turning attention to metaanalyses. This may be positive in light of the many underpowered studies that have been reported. However, one must step back and put this activity in perspective and not lose sight of the important role of the clinical trial in research. Further e