Methionine-auxotrophic L1210 cells were used to study the effect of methotrexate (MTX) on methionine uptake and metabolism. MTX was shown to inhibit amino acid transport systems and cause a decrease of methionine uptake into L1210 cells. Conversely, a nonmetabolizable amino acid analogue reduced MTX
✦ LIBER ✦
Mechanisms of Inhibition of Amido Phosphoribosyltransferase from Mouse L1210 Leukemia Cells †
✍ Scribed by Schoettle, Sarah L.; Crisp, Leesa B.; Szabados, Eve; Christopherson, Richard I.
- Book ID
- 126017816
- Publisher
- American Chemical Society
- Year
- 1997
- Tongue
- English
- Weight
- 258 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0006-2960
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