𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Mechanism of DNA-binding loss upon single-point mutation in p53

✍ Scribed by Jon D. Wright; Carmay Lim

Book ID
107583026
Publisher
Indian Academy of Sciences
Year
2007
Tongue
English
Weight
416 KB
Volume
32
Category
Article
ISSN
0250-5991

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Lack of allelic deletion and point mutat
Lack of allelic deletion and point mutation as mechanisms of p53 activation in human malignant melanoma
✍ Javier S. Castresana; Mari-Paz Rubio; Bernd R. Seizinger; J. Jaime VΓ zquez; Migu πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 French βš– 492 KB

To investigate the role of the p53 tumor-suppressor gene in the development of human melanoma, loss of heterozygosity (LOH) of p53 was studied in 46 cases of melanoma by a polymerase-chain-reaction/restriction-fragment-len~h polymorphism (PCR/RFLP) analysis, and p53 mutations were assessed in 5 I ca

Effect of heterozygous loss of p53 on be
Effect of heterozygous loss of p53 on benzo[a]pyrene-induced mutations and tumors in DNA repair-deficient XPA mice
✍ Conny Th. M. van Oostrom; Miranda Boeve; Jolanda van den Berg; Annemieke de Vrie πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 130 KB πŸ‘ 3 views

XPA-deficient mice have a complete deficiency in nucleotide excision repair, and as such they display a cancer predisposition after exposure to several carcinogens. Besides being sensitive to genotoxic agents applied to the skin, they are also susceptible to human carcinogens given orally, like benz