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Detection of point mutations in the p53 gene: Comparison of single-strand conformation polymorphism, constant denaturant gel electrophoresis, and hydroxylamine and osmium tetroxide techniques

โœ Scribed by Alison Condie; Rosalind Eeles; Anne-Lise Borresen; Christopher Coles; Colin Cooper; Jane Prosser


Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
768 KB
Volume
2
Category
Article
ISSN
1059-7794

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## Detection of mutations and polymorphisms in the p53 tumor suppressor gene by single-strand conformation polymorphism analysis Deciphering the genetic mechanisms in cancer development requires analysis of a large number of tumors for consistent genetic alterations. Single-strand conformational p