Measurements of heteronuclear long-range coupling constants from inverse homonuclear 2D NMR spectra
β Scribed by U Wollborn; D Leibfritz
- Publisher
- Elsevier Science
- Year
- 1992
- Weight
- 260 KB
- Volume
- 98
- Category
- Article
- ISSN
- 0022-2364
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π SIMILAR VOLUMES
Coupling constants in proton systems provide access to useful structural information. Several methods have been proposed to measure these constants in high-resolution spectra, but many of them are not well suited when the coupling constants are comparable to the spectral linewidth. In such a case th
Long-range heteronuclear coupling constants, n J XH , have been recognized as an important source of information in the structural elucidation of molecules (1). Accordingly, a large number of methods for their measurement have been proposed to date . Often these methods rely on the characteristic sp
A simple pulse sequence in inverse-detection mode is proposed for the detection of heteronuclear long-range couplings. In the resulting 2D heteronuclear multiple-bond correlation (HMBC) spectra, pure-absorptive peak patterns are obtained along both frequency dimensions. Since the heteronuclear coupl