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Measurement of the Kinetics of Protein Unfolding in Viscous Systems and Implications for Protein Stability in Freeze-Drying

โœ Scribed by Xiaolin (Charlie) Tang; Michael J. Pikal

Book ID
106492623
Publisher
Springer US
Year
2005
Tongue
English
Weight
561 KB
Volume
22
Category
Article
ISSN
0724-8741

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โœ Schwegman, J. Jeff (author);Carpenter, John F. (author);Nail, Steven L. (author) ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons Inc. ๐ŸŒ English โš– 279 KB

A commercially available freeze-dry microscopy stage interfaced with an IR microscope is described as a method of in situ measurement of protein secondary structure in the liquid, frozen and freeze-dried states. Studies using solutions of model proteins demonstrated that spectra collected using the