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The Effect of Stabilizers and Denaturants on the Cold Denaturation Temperatures of Proteins and Implications for Freeze-Drying

✍ Scribed by Xiaolin (Charlie) Tang; Michael J. Pikal

Publisher
Springer US
Year
2005
Tongue
English
Weight
444 KB
Volume
22
Category
Article
ISSN
0724-8741

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The particle volume of a protein which represents the expansion of the molecular chain is a useful probe to measure its conformation change in solution. To study the details of the conformation transition, we will report a novel device to trace the particle-volume change against increasing denaturan