MEASUREMENT OF BLOOD-BRAIN BARRIER PERMEABILITY
✍ Scribed by P. J. Robinson
- Book ID
- 108934893
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 830 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0305-1870
No coin nor oath required. For personal study only.
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## Abstract Two recently published methods of blood‐brain barrier permeability measurement using Gd‐DTPA scanning are compared by authors representing each group. The physiological models are reconciled. Results from both groups agree. These show that the transfer constant (the permeability surface
## Abstract Sequential MR imaging with gadolinium‐diethylenetriaminepentaacetic acid (Gd‐DTPA) and sequential measurements of plasma Gd‐DTPA concentration by inductively coupled plasma atomic emission spectroscopy (ICP‐AES) were used to estimate the blood‐to‐tissue transport coefficient (K~i~) in t
## Abstract Breakdown of the blood‐brain barrier (BBB), occurring in many neurological diseases, has been difficult to measure noninvasively in humans. Dynamic contrast‐enhanced magnetic resonance imaging measures BBB permeability. However, important technical challenges remain and normative data f