๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Mean time parameters dealing with the tissue distribution of drugs: Limitations and extensions

โœ Scribed by Peter Veng-Pedersen


Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
332 KB
Volume
78
Category
Article
ISSN
0022-3549

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Determination of mean residence time of
โœ Leonid M. Berezhkovskiy ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 199 KB ๐Ÿ‘ 1 views

The equation for the calculation of mean residence time of drug in plasma, t(p), is obtained. It is shown that the previously suggested calculation of t(p) considerably overestimates the true value in most cases. It is suggested that due to the possible initial (before establishing the uniform drug

A general method for calculating the mea
โœ Haiyung Cheng ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 341 KB ๐Ÿ‘ 2 views

A general method for calculating the mean transit times and distribution rate parameters is described. The calculations require the AUC, AUMC, and derivatives of the plasma concentration profiles of the metabolites and its precursor. The method is applicable to catenary metabolites with any precurso

Mean residence time of drugs administere
โœ Haiyung Cheng ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 409 KB ๐Ÿ‘ 2 views

Based on disposition decomposition analysis (DDA), equations for the mean residence times (MRT) in the body are derived for a drug and its interconversion metabolite that undergo linear tissue distribution and linear or non-linear elimination from the central compartment after non-instantaneous admi