Marked enhancement of interferon production in 5-bromodeoxyuridine treated human lymphoblastoid cells
β Scribed by TOVEY, MICHAEL G.; BEGON-LOURS, JACQUELINE; GRESSER, ION; MORRIS, ALAN G.
- Book ID
- 109705034
- Publisher
- Nature Publishing Group
- Year
- 1977
- Tongue
- English
- Weight
- 328 KB
- Volume
- 267
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/267455a0
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The authors found remarkable enhancement of Inoue-Melnick virus (IMV) synthesis b y 5bromodeoxyuridine (BUDR) in human meningioma (MG-1) cells, a virus-producer line of type 1 IMV. Treatment with BUDR resulted in rapid and abundant synthesis of infectious IMV in MG-1 cells. The titer of the cell-ass
## Abstract InoueβMelnick virus (IMV) synthesis in naturally infected human colon carcinoma cell lines can be enhanced by 5βbromodeoxyurdine (BUDR). The optimal conditions for BUDR enhancement differed between two cell lines, SWβ480 and DLDβ1, SWβ480 cells produced 100 times more infectious IMV tha