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Inhibitor of 2′,5′-oligoadenylate synthetase induced in human T lymphoblastoid cell line treated with deoxyadenosine, deoxycoformycin and interferon

✍ Scribed by T. Heike; K. Katamura; M. Kubota; K. Shinomiya; H. Mikawa


Book ID
118509260
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
330 KB
Volume
127
Category
Article
ISSN
0006-291X

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## Abstract Human α interferon (IFN‐α) and β interferon (IFN‐β) showed antiviral and anticellular effects on human lymphoblastoid Daudi and P3HR‐1 cells, but up to 1,000 units/ ml of γ interferon (IFN‐γ) showed no such effect. Though a fairly high level of dsRNA‐dependent 2′‐5′‐oligoadenylate synth