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Mammalian recombination-repair genes XRCC2 and XRCC3 promote correct chromosome segregation

✍ Scribed by Thacker, John; Griffin, Carol S.; Simpson, Paul J.; Wilson, Caroline R.


Book ID
109771083
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
866 KB
Volume
2
Category
Article
ISSN
1465-7392

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DNA repair gene XRCC2 and XRCC3 polymorp
✍ Simone Benhamou; Jarno Tuimala; Christine Bouchardy; Pierre Dayer; Alain Sarasin πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 French βš– 71 KB πŸ‘ 1 views

## Abstract Cigarette smoke can generate reactive oxygen species, which are capable of inducing double‐strand breaks (DSBs) in DNA. Polymorphisms in __XRCC2__ and __XRCC3__ genes, involved in DSBs repair pathways, may alter an individual's susceptibility to smoking‐related cancers. We investigated