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Polymorphism of the homologous recombination repair genes RAD51 and XRCC3 in breast cancer

✍ Scribed by Renata Krupa; Ewelina Synowiec; Elzbieta Pawlowska; Zbigniew Morawiec; Anna Sobczuk; Marek Zadrozny; Katarzyna Wozniak; Janusz Blasiak


Book ID
113956631
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
146 KB
Volume
87
Category
Article
ISSN
0014-4800

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Polymorphisms inRAD51, XRCC2andXRCC3gene
✍ Renata Krupa; Tomasz Sliwinski; Maria Wisniewska-Jarosinska; Jan Chojnacki; Maja πŸ“‚ Article πŸ“… 2010 πŸ› Springer 🌐 English βš– 241 KB

XRCC2 and XRCC3 proteins are structurally and functionally related to RAD51 which play an important role in the homologous recombination, the process frequently involved in cancer transformation. In our previous work we show that the 135G>C polymorphism (rs1801320) of the __RAD51__ gene can modify t