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918 Polymorphisms of the DNA Repair Genes Rad51, Xrcc2, Xrcc3 in Inflammatory Bowel Diseases and Colorectal Cancer

✍ Scribed by Maria A. Wisniewska-Jarosinska; Tomasz Sliwinski; Justyna Lech; Krystyna Stec-Michalska; Jan Chojnacki; Janusz Blasiak

Book ID: 119428492
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 69 KB
Volume: 134
Category: Article
ISSN: 0016-5085
DOI: 10.1016/s0016-5085(08)60618-6

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## Abstract Cigarette smoke can generate reactive oxygen species, which are capable of inducing double‐strand breaks (DSBs) in DNA. Polymorphisms in __XRCC2__ and __XRCC3__ genes, involved in DSBs repair pathways, may alter an individual's susceptibility to smoking‐related cancers. We investigated

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