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Major contribution of codominant CD8 and CD4 T cell epitopes to the human cytomegalovirus-specific T cell repertoire

✍ Scribed by M. -D. Nastke†; L. Herrgen†; S. Walter; D. Wernet; H. -G. Rammensee; S. Stevanović


Publisher
Springer
Year
2005
Tongue
English
Weight
168 KB
Volume
62
Category
Article
ISSN
1420-682X

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## Abstract Spontaneous tumors frequently express antigens that can be recognized by the immune system but nevertheless manage to evade immune surveillance. To better understand the mechanism of evasion, we followed CD8 and CD4 T cells reacting against a subcutaneously growing tumor, modified to ex