Nonpolymorphic interactions between the T cell differentiation antigens CD4 or CD8 and major histocompatibility complex (MHC)-encoded molecules have been postulated to participate in antigen recognition of MHC-restricted T cells. This would imply simultaneous binding of CD418 and of the T cell recep
β¦ LIBER β¦
Cross-linking of CD4 and CD8 with the T-cell receptor complex: quaternary complex formation and T-cell repertoire selection
β Scribed by F. Emmrich
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 763 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0167-5699
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## Weak positive selection of transgenic T cell receptor-bearing thymocytes: importance of major histocompatibility complex class 11, T cell receptor and CD4 surface molecule densities* We have produced up Tcell receptor (TcR)-transgenic mice and studied MHC-dependent positive selection of T cells