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LRRK2 mutations in Parkinson's disease: Confirmation of a gender effect in the Italian population

✍ Scribed by Cilia, Roberto; Siri, Chiara; Rusconi, Damiana; Allegra, Roberta; Ghiglietti, Andrea; Sacilotto, Giorgio; Zini, Michela; Zecchinelli, Anna L.; Asselta, Rosanna; Duga, Stefano; Paganoni, Anna M.; Pezzoli, Gianni; Seia, Manuela; Goldwurm, Stefano


Book ID
122223396
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
209 KB
Volume
20
Category
Article
ISSN
1353-8020

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Frequency and phenotypes of LRRK2 G2019S
✍ Roberta Marongiu; Daniele Ghezzi; Tamara Ialongo; Francesco Soleti; Antonio Elia πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 74 KB

To evaluate the frequency of the LRRK2 G2019S mutation in Italy, we tested 1,072 probands with Parkinson's disease (PD; 822 sporadic and 250 familial): 20 patients (1.9%) carried the G2019S mutation, 11 patients (1.3%) were sporadic, and 9 (4.3%) had a positive family history. Considering only proba