A common LRRK2 mutation in idiopathic Parkinson's disease
β Scribed by William P Gilks; Patrick M Abou-Sleiman; Sonia Gandhi; Shushant Jain; Andrew Singleton; Andrew J Lees; Karen Shaw; Kailash P Bhatia; Vincenzo Bonifati; Niall P Quinn; John Lynch; Daniel G Healy; Janice L Holton; Tamas Revesz; Nicholas W Wood
- Book ID
- 117287747
- Publisher
- The Lancet
- Year
- 2005
- Tongue
- English
- Weight
- 208 KB
- Volume
- 365
- Category
- Article
- ISSN
- 0140-6736
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π SIMILAR VOLUMES
## Abstract The G2019S mutation in the __LRRK2__ gene is reportedly a common cause of familial Parkinson's disease (PD) and may also have a significant role in nonfamilial PD. The objective of this study was to assess mutation carrier frequency in PD patients from movement disorder clinics in the U
## Abstract We determined the prevalence of two common leucineβrich repeat kinase 2 (LRRK2) gene mutations in Australian patients with Parkinson's disease (PD). Of 830 affected patients, eight were heterozygous for the G2019S mutation, and two were heterozygous for the R1441H (4,322 G > A) mutation