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Low frequency of common LRRK2 mutations in Mexican patients with Parkinson's disease

✍ Scribed by Petra Yescas; Marisol López; Nancy Monroy; Marie-Catherine Boll; Mayela Rodríguez-Violante; Ulises Rodríguez; Adriana Ochoa; María Elisa Alonso


Book ID
116772557
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
191 KB
Volume
485
Category
Article
ISSN
0304-3940

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To evaluate the frequency of the LRRK2 G2019S mutation in Italy, we tested 1,072 probands with Parkinson's disease (PD; 822 sporadic and 250 familial): 20 patients (1.9%) carried the G2019S mutation, 11 patients (1.3%) were sporadic, and 9 (4.3%) had a positive family history. Considering only proba

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