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Genetic analysis of LRRK2 mutations in patients with Parkinson disease

✍ Scribed by Hao Deng; WeiDong Le; Yi Guo; Christine B. Hunter; WenJie Xie; MaoSheng Huang; Joseph Jankovic


Book ID
119302112
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
237 KB
Volume
251
Category
Article
ISSN
0022-510X

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## Abstract Mutations in the leucine‐rich repeat kinase 2 (__LRRK2__) gene are the most common genetic determinant of Parkinson's disease (PD) in European‐derived populations, but far less is known about __LRRK2__ mutations and susceptibility alleles in Asians. To address this issue, we sequenced t