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Loss of IGF2 Imprinting: A Potential Marker of Colorectal Cancer Risk

✍ Scribed by Cui, H.

Book ID
124157075
Publisher
American Association for the Advancement of Science
Year
2003
Tongue
English
Weight
218 KB
Volume
299
Category
Article
ISSN
0036-8075

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## Abstract Loss of imprinting (LOI) of insulin‐like growth factor 2 (__IGF2__) is a common event in many cancers and typically activates the maternally silenced allele. The resulting biallelic __IGF2__ expression correlates strongly with the hypomethylation of a differentially methylated region (D