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Loss of Heterozygosity of Chromosome 10p in Human Gliomas

✍ Scribed by Alec C. Kimmelman; Donald A. Ross; Bertrand C. Liang


Book ID
115613233
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
143 KB
Volume
34
Category
Article
ISSN
0888-7543

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Cytogenetic and RFLP studies have shown that chromosome I0 is frequently lost in tumor cells from glioblastomas, suggesting that a suppressor gene important in tumorigenesis is present on this chromosome. Forty-one tumors were examined for loss of heterozygosity at 23 loci on chromosome 10 to determ

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