Loss of constitutional heterozygosity in
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K. Watanabe; M. Nagai; S. Wakai; T. Arai; K. Kawashima
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Article
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1990
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Springer-Verlag
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English
β 413 KB
Gene deletion of chromosome 10 in 11 tumor tissues removed from nine patients with malignant glioma (seven glioblastomas and two malignant astrocytomas) was investigated. Loss of heterozygosity was found in four of the seven (57%) cases with glioblastoma, whereas heterozygosity was preserved in two