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Loss of heterozygosity on chromosome 10 in human glioblastoma multiforme

✍ Scribed by Fujimoto, Masahito; Fults, Daniel W.; Thomas, Gregory A.; Nakamura, Yusuke; Heilbrun, M.Peter; White, Ray; Story, Jim L.; Naylor, Susan L.; Kagan-Hallet, Kathleen S.; Sheridan, Peter J.


Book ID
122676838
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
564 KB
Volume
4
Category
Article
ISSN
0888-7543

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Loss of constitutional heterozygosity in
✍ K. Watanabe; M. Nagai; S. Wakai; T. Arai; K. Kawashima πŸ“‚ Article πŸ“… 1990 πŸ› Springer-Verlag 🌐 English βš– 413 KB

Gene deletion of chromosome 10 in 11 tumor tissues removed from nine patients with malignant glioma (seven glioblastomas and two malignant astrocytomas) was investigated. Loss of heterozygosity was found in four of the seven (57%) cases with glioblastoma, whereas heterozygosity was preserved in two