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Loss of heterozygosity atBRCA1/2loci in hereditary and sporadic ovarian cancers

✍ Scribed by I. Brożek; K. Ochman; J. Dębniak; L. Morzuch; M. Ratajska; M. Stepnowska; M. Stukan; J. Emerich; J. Limon


Publisher
Springer-Verlag
Year
2009
Tongue
English
Weight
112 KB
Volume
50
Category
Article
ISSN
1234-1983

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## Abstract Frequent loss of heterozygosity (LOH) on both arms of chromosome 17 has been described in ovarian carcinoma (OC) by a number of groups, and the recent fine mapping of an inherited breast‐ovarian cancer gene (__brc__Al) to a small region at 17q 12–21 has focused interest on this area. We