BRCA1 is considered to be a tumor-suppressor gene, yet mutations in this gene are uncommon in sporadic breast tumors. We investigated whether mechanisms other than DNA mutations that affect the coding region might be involved in breast carcinogenesis. Since loss of expression of the BRCA1 gene would
Frequent loss of BRCA1 mRNA and protein expression in sporadic ovarian cancers
β Scribed by Paul A. Russell; Paul D.P. Pharoah; Karen De Foy; Susan J. Ramus; Ian Symmonds; Annie Wilson; Ian Scott; Bruce A.J. Ponder; Simon A. Gayther
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- French
- Weight
- 307 KB
- Volume
- 87
- Category
- Article
- ISSN
- 0020-7136
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