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Loss of heterozygosity at chromosome 11P and tumour progression in non-small cell lung cancer

✍ Scribed by Fong, K.M.; Zimmerman, P.V.; Smith, P.J.


Book ID
122452902
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
135 KB
Volume
11
Category
Article
ISSN
0169-5002

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Correlation of loss of heterozygosity at
✍ Kwun M. Fong; Paul V. Zimmerman; Peter J. Smith πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 523 KB

Loss of heterozygosity (LOH) affecting loci at I I p I 3 and I I p I 5 occurs in childhood and adult carcinomas, including non-small cell lung cancer (NSCLC). In NSCLC, the highest reported frequency of LOH was 72% at the I I p I 3 catalase (CAT) locus. As this locus is centromeric t o the Wilms' tu