Loss of heterozygosity of chromosome 12p
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Mika Uchiyama; Noriyasu Usami; Masashi Kondo; Shoichi Mori; Masao Ito; Genshi It
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Article
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2003
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John Wiley and Sons
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French
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## Abstract Activating mutations of __RAS__ gene families have been found in a variety of human malignancies, including lung cancer, suggesting their dominant role in tumorigenesis. However, several studies have shown a frequent loss of the wildโtype __KRAS__ allele in the tumors of murine models a