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Tumor progression and loss of heterozygosity at 5q and 18q in non-small cell lung cancer


Book ID
122983319
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
137 KB
Volume
12
Category
Article
ISSN
0169-5002

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LOSS OF HETEROZYGOSITY AT 5q21 IN NON-SM
✍ COOPER, CINDY A.; BUBB, VIVIEN J.; SMITHSON, NICOLA; CARTER, ROBERT L.; GLEDHILL πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 538 KB

Four genetic poljmorphisms in the AP C and MCC genes at chromosome 5q21 were analysed for loss of heterozygosity &OH) in 97 primary squamous carcinomas and adenocarcinomas of the lung. LOH was identified in at least two polymorphic loci in 41 percent of informative cases. There was no significant di