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50 O - Loss of heterozygosity (LOH) AT 5q21 and prognosis in resected non-small cell lung cancer (NSCLC)

✍ Scribed by M. Sánchez; J.L. Mate; I. Moreno; M.P. López; A.I. Aldea; J. Astudillo; M. Monzó; R. Rosell


Book ID
116168327
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
189 KB
Volume
32
Category
Article
ISSN
0959-8049

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LOSS OF HETEROZYGOSITY AT 5q21 IN NON-SM
✍ COOPER, CINDY A.; BUBB, VIVIEN J.; SMITHSON, NICOLA; CARTER, ROBERT L.; GLEDHILL 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 538 KB

Four genetic poljmorphisms in the AP C and MCC genes at chromosome 5q21 were analysed for loss of heterozygosity &OH) in 97 primary squamous carcinomas and adenocarcinomas of the lung. LOH was identified in at least two polymorphic loci in 41 percent of informative cases. There was no significant di