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Long-Range Communication between Chromatin and Microtubules in Xenopus Egg Extracts

✍ Scribed by Rafael E. Carazo-Salas; Eric Karsenti


Book ID
113558447
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
386 KB
Volume
13
Category
Article
ISSN
0960-9822

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The role of SV40 large tumor T-antigen in replication of viral DNA is well established, but it is still unclear how T-antigen triggers cellular replication and cell transformation in non-permissive cells. Here, we used Xenopus egg extracts which reproduce most nuclear events linked to the cell cycle