Electrosynthetic modification of protein
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David J. Walton; Paul G. Richards; John Heptinstall; Brian Coles
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Article
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1997
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Elsevier Science
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English
β 808 KB
Electrosynthesis provides a novel methodology to produce specific and selective chemical reaction in proteins. Thus electrooxidation of hen egg-white lysozyme (HEWL) at + 1.2 V (vs see) at a carbon anode in mildly acid buffer produces selective oxidation at methionine-105; while by increase in anodi