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Analysis of microtubule polymerization in vitro and during the cell cycle in Xenopus egg extracts

✍ Scribed by Priya Prakash Budde; Arshad Desai; Rebecca Heald


Book ID
116986613
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
219 KB
Volume
38
Category
Article
ISSN
1046-2023

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The role of SV40 large tumor T-antigen in replication of viral DNA is well established, but it is still unclear how T-antigen triggers cellular replication and cell transformation in non-permissive cells. Here, we used Xenopus egg extracts which reproduce most nuclear events linked to the cell cycle