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Localization of Thymidine Phosphorylase in Advanced Gastric and Colorectal Cancer

โœ Scribed by Michiya Kobayashi; Ken Okamoto; Toyokazu Akimori; Naoshige Tochika; Tadashi Yoshimoto; Takehiro Okabayashi; Takeki Sugimoto; Keijiro Araki


Book ID
111584373
Publisher
Springer
Year
2003
Tongue
English
Weight
329 KB
Volume
35
Category
Article
ISSN
1567-2379

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Thymidine phosphorylase and dihydropyrim
โœ Elaina S.R. Collie-Duguid; Stephen J. Johnston; Linda Boyce; Nicola Smith; Aaron ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 96 KB

It is essential for actively proliferating cells to increase their rate of DNA synthesis to progress through the cell cycle. This is reflected in the increased uracil usage that is a common feature in solid tumours. Thymidine phosphorylase (TP) anabolises formation of pyrimidine nucleosides availabl