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Expression of thymidylate synthase and thymidine phosphorylase in recurrence and survival rates of advanced gastric cancer

โœ Scribed by Yasuo Suda; Yoshio Kuwashima; Yoichi Tanaka; Kenji Uchida; Hirohiko Sakamoto; Yojiro Hashiguchi; Takeshi Sekine

Book ID
106281288
Publisher
Springer
Year
1999
Tongue
English
Weight
112 KB
Volume
2
Category
Article
ISSN
1436-3291

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## Abstract Thymidylate synthase (TS) and dihydropyrimidine dehydrogenase (DPD) are important enzymes of DNA __de novo__ synthesis and the salvage pathway in cancer cells, respectively. Intratumoral TS and DPD gene expressions were evaluated to determine the correlation between the expression of th

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## Background: Thymidine phosphorylase (tp) has angiogenic activity in various cancer tissues. gastric carcinomas are classified into two histologic groups: differentiated and undifferentiated adenocarcinomas. there are differences in the modes of development and the extent of infiltration between